TY - JOUR T1 - Genetic scrambling as a defence against meiotic drive JF - J Theor Biol Y1 - 1991 A1 - Haig, D. A1 - Grafen, A. KW - *Models, Genetic KW - Alleles KW - Biological Evolution KW - Meiosis/*genetics KW - Recombination, Genetic/*physiology AB -

Genetic recombination has important consequences, including the familiar rules of Mendelian genetics. Here we present a new argument for the evolutionary function of recombination based on the hypothesis that meiotic drive systems continually arise to threaten the fairness of meiosis. These drive systems act at the expense of the fitness of the organism as a whole for the benefit of the genes involved. We show that genes increasing crossing over are favoured, in the process of breaking up drive systems and reducing the fitness loss to organisms.

VL - 153 SN - 0022-5193 (Print)0022-5193 (Linking) N1 -

Haig, DGrafen, AengENGLAND1991/12/21J Theor Biol. 1991 Dec 21;153(4):531-58.

JO - Journal of theoretical biologyJournal of theoretical biology ER -